Optical Diagnostics in Human Diseases

Functional diagnostics in mitochondrial diseases.

Mitochondrial diseases (MD) with respiratory chain defects are caused by genetic mutations that determine an impairment of the electron transport chain functioning. Diagnosis often requires a complex approach with measurements of serum lactate, magnetic resonance spectroscopy (MRS), muscle histology and ultrastructure, enzymology, genetic analysis, and exercise testing. The ubiquitous distribut...

Optical Techniques in Plasma Diagnostics

Recent developments in optical techniques for plasma diagnostics are critically reviewed. The primary emphasis is on plasma-induced emission and laser-induced fluorescence probes of radical and ionic concentrations and temperatures in low pressure discharges like those used in microelectronic fabrication. Other techniques such as optogalvanic, infrared, spontaneous and stimulated Raman, and mul...

Multivesicular liposome (DepoFoam) in human diseases

Drug development is a key point in the research of new therapeutic treatments for increasing maximum drug loading and prolonged drug effect. Encapsulation of drugs into multivesicular liposomes (DepoFoam) is a nanotechnology that allow deliver of the active constituent at a sufficient concentration during the entire treatment period. This guarantees the reduction of drug administration frequenc...

Optical Diagnostics within La3net*

The Laser Applications at Accelerators network (LA3NET) is a pan-European project that has received 4.6 M€ of funding from the European Union's 7th Framework Programme. It closely links research into lasers and accelerators to develop advanced particle sources, new accelerating schemes, and in particular beyond state-ofthe-art beam diagnostics. This contribution summarizes the research achievem...

Optical Biomedical Diagnostics